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Cell and animal evidence

MOTS-C research overview

Review the published research context, areas studied and evidence limitations associated with this catalogue material.

Evidence context statedSources linkedLast reviewed

Research context

Cell and animal studies have examined MOTS-C as a mitochondrially encoded signalling peptide in metabolic homeostasis, cellular stress responses and mitonuclear communication.

Areas studied

  • Mitochondrial-derived peptide signalling
  • Cellular metabolic homeostasis
  • AMPK-linked stress responses
  • Mitonuclear communication

Limitations and investigational status

The cited work is principally mechanistic cell research and animal research. Findings from these experimental systems do not establish effects in humans.

References

  1. 1Lee et al. — Cell Metabolism, 2015
  2. 2Kim et al. — Cell Metabolism, 2018

For laboratory research use only. Information presented here summarises areas investigated in published research and is not intended as medical advice or as evidence of established effects in humans.